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Multisystem Atrophy


MSA Diagnosis

Physician-developed and -monitored.

Original Date of Publication: 02 Jan 2000
Reviewed by: Stanley J. Swierzewski, III, M.D.
Last Reviewed: 04 Dec 2007

Original Source: http://www.neurologychannel.com/msa/diagnosis.shtml

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MSA Diagnosis



Differentiating MSA from Parkinson's disease can be difficult. Diagnosis is often based on evaluating clinical symptoms and conducting brain imaging. After death, MSA can easily be identified by pathological examination of the brain tissue during autopsy.

Striatonigral degeneration, in particular, is often misdiagnosed as Parkinson's since the clinical symptoms are so similar. The most noticeable difference is that it does not respond to Parkinson's treatment. In some cases, its characteristic cerebellar atrophy (wasting of the cerebellum) can be viewed on an MRI scan, CT scan, or PET scan.

Other disorders (e.g., tumors, multiple sclerosis, alcoholism) can be confused with MSA.


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